A Population Dynamics Model for Clonal Diversity in a Germinal Center

@inproceedings{Amitai2017APD,
  title={A Population Dynamics Model for Clonal Diversity in a Germinal Center},
  author={Assaf Amitai and Luka Mesin and Gabriel D. Victora and Mehran Kardar and Arup K. Chakraborty},
  booktitle={Front. Microbiol.},
  year={2017}
}
Germinal centers (GCs) are micro-domains where B cells mature to develop high affinity antibodies. Inside a GC, B cells compete for antigen and T cell help, and the successful ones continue to evolve. New experimental results suggest that, under identical conditions, a wide spectrum of clonal diversity is observed in different GCs, and high affinity B cells… CONTINUE READING