A Polyketide Synthase Component for Oxygen Insertion into Polyketide Backbones.

@article{Meoded2018APS,
  title={A Polyketide Synthase Component for Oxygen Insertion into Polyketide Backbones.},
  author={Roy A Meoded and Reiko Ueoka and Eric Jan Nikolaus Helfrich and Katja Jensen and Nancy Magnus and Birgit Piechulla and J{\"o}rn Piel},
  journal={Angewandte Chemie},
  year={2018}
}
Enzymatic core components from trans-acyltransferase polyketide synthases (trans-AT PKSs) catalyze exceptionally diverse biosynthetic transformations to generate structurally complex bioactive compounds. Here we focus on a group of oxygenases identified in various trans-AT PKS pathways, including those for pederin, oocydins, and toblerols. Using the oocydin… CONTINUE READING