A Polycomb response element in the Ubx gene that determines an epigenetically inherited state of repression.

@article{Chan1994APR,
  title={A Polycomb response element in the Ubx gene that determines an epigenetically inherited state of repression.},
  author={Clarence S.M. Chan and Luca Rastelli and Vincenzo Pirrotta},
  journal={The EMBO journal},
  year={1994},
  volume={13 11},
  pages={
          2553-64
        }
}
Segmentation genes provide the signals for the activation and regulation of homeotic genes in Drosophila but cannot maintain the resulting pattern of expression because their activity ceases halfway through embryogenesis. Maintenance of the pattern is due to the Polycomb group of genes (Pc-G) and the trithorax group of genes (trx-G), responsible for the persistence of the active or repressed state of homeotic genes. We have identified a regulatory element in the Ubx gene that responds to Pc-G… CONTINUE READING
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