A Plasma Metabolomic Investigation of Colorectal Cancer Patients by Liquid Chromatography-Mass Spectrometry

@inproceedings{Fukui2010APM,
  title={A Plasma Metabolomic Investigation of Colorectal Cancer Patients by Liquid Chromatography-Mass Spectrometry},
  author={Yousuke Fukui and Kohji Itoh},
  year={2010}
}
Due to hypoxic conditions, colorectal cancer (CRC) tissues have a specific metabolism compared with normal mucosa, and this study aimed to investigate blood plasma metabolite differences between CRC patients and healthy subjects. Non-targeted methods have previously been used to characterize CRC disease diagnosis and identify small molecules in biological samples, but here we used a metabolomic approach based on liquid chromatography-mass spectrometry (LC-MS) of blood plasma from CRC patients… CONTINUE READING

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