A Plant-Like Kinase in Plasmodium falciparum Regulates Parasite Egress from Erythrocytes
@article{Dvorin2010APK, title={A Plant-Like Kinase in Plasmodium falciparum Regulates Parasite Egress from Erythrocytes}, author={J. Dvorin and Derek C. Martyn and Saurabh D. Patel and J. S. Grimley and C. Collins and Christine S. Hopp and A. Bright and S. Westenberger and E. Winzeler and M. Blackman and D. Baker and T. Wandless and M. Duraisingh}, journal={Science}, year={2010}, volume={328}, pages={910 - 912} }
It's a Knockout The malaria parasite is one of the most important pathogens of humans. Increasing drug-resistance is an imminent public health disaster, and we urgently need to find new drugs. The recently acquired malarial genomes provide a plethora of targets. However, due to the genetic intractability of the parasite, it has been difficult to identify essential genes in the clinically relevant blood-stage of the parasite. Dvorin et al. (p. 910) investigated the function of a Plasmodium… CONTINUE READING
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