A Pilot Study Evaluating Dental Research Enrollment in Four Multicenter Clinical Research Trials

  title={A Pilot Study Evaluating Dental Research Enrollment in Four Multicenter Clinical Research Trials},
  author={Rebecca Showalter and Carol A. Nguyen and W. W. Jr. Curtis and JoAnn Diaz Jordan and Melanie V. Taverna},
  journal={Clinical researcher},
When the managers of a periodontal clinical trial experienced a large gap between the projected number and the actual number of enrolled subjects within a planned time period, successful completion of the research was threatened.[1][1] This gap occurred when inclusion and exclusion criteria were too 


Subject recruitment, retention, and compliance in clinical trials in periodontics.
The recruitment process can be complicated by legal requirements of proper representation of sex and race characteristics or by stringent entry criteria, and complex designs have not yet shown to be cost-effective and may endanger recruitment success.
The advantages and disadvantages of running a clinical trial in general practices
The experiences encountered in running a clinical trial on the use of a metal reinforced glass-ionomer cement in general dental practices imply that there can be major problems in undertaking clinical trials of this nature in the general dental service.
The Prevalence and Economic Impact of Low-Enrolling Clinical Studies at an Academic Medical Center
Although a certain percentage of low-enrolling studies can be expected in any research organization, the overall number of such studies must be managed to reduce the aggregate costs of conducting research and to maximize research opportunities.
Considerations in the statistical analysis of clinical trials in periodontitis.
  • P. Imrey
  • Psychology
    Journal of clinical periodontology
  • 1986
This paper comments, with varying degrees of emphasis, on several issues pertinent to the analysis of periodontal trials, including the ways in which measurement variability may distort analytic results.
Protecting Human Research Participants
Research with human subjects can occasionally result in a dilemma for investigators. When the goals of the research are designed to make major contributions to a field, such as improving the