A Physiologic Approach to the Pharmacogenomics of Hypertension.

  title={A Physiologic Approach to the Pharmacogenomics of Hypertension.},
  author={Michael T Eadon and Arlene B. Chapman},
  journal={Advances in chronic kidney disease},
  volume={23 2},
Hypertension is a multifactorial condition with diverse physiological systems contributing to its pathogenesis. Individuals exhibit significant variation in their response to antihypertensive agents. Traditional markers, such as age, gender, diet, plasma renin level, and ethnicity, aid in drug selection. However, this review explores the contribution of genetics to facilitate antihypertensive agent selection and predict treatment efficacy. The findings, reproducibility, and limitations of… CONTINUE READING


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