A Photostable Pyrethroid

@article{Elliott1973APP,
  title={A Photostable Pyrethroid},
  author={Michael Elliott and Andrew W. Farnham and Norman Frank Janes and P. H. Needham and David A. Pulman and John H. Stevenson},
  journal={Nature},
  year={1973},
  volume={246},
  pages={169-170}
}
THE natural pyrethrins (see refs 1 and 2 for references) (for example, pyrethrin I (1)) and related synthetic insecticides3 (allethrin (2), bioallethrin (3), resmethrin (4), bioresmethrin (5), Cismethrin (6) and the ethanochrysanthemate (7)) are unstable in air and light (see refs 1 and 2 for references, and ref. 4). This property restricts their use, particularly against pests of agricultural crops, in spite of other favourable characteristics (see refs 1–3 for references) (outstanding potency… Expand
Action of pyrethroids.
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In the last decennium great progress has been made in the development of more stable and highly active pyrethroids and in the near future more widespread application of these compounds may be expected. Expand
Effects of synthetic pyrethroid insecticides on nontarget organisms.
TLDR
Synthetic pyrethroids are much less persistent than the organochlorine insecticides, such as DDT and dieldrin, and apparently do not accumulate in the environment. Expand
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  • Xenobiotica; the fate of foreign compounds in biological systems
  • 1992
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Initial tests indicate that even the more stable compounds are degraded rapidly in soil, so if the trials at present in progress reveal no toxicological or environmental hazards, within a few years synthetic pyrethroids should be available to control a wide range of domestic, veterinary, horticultural, agricultural, and forest pests at low rates of application. Expand
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  • Biology, Medicine
  • The Southeast Asian journal of tropical medicine and public health
  • 1992
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Beta-cyfluthrin is a good insecticide for mosquito control, however, care should be exercised while using it as a larvicide in breeding habitats considering its toxicity to fish. Expand
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Evaluating different classes of 2-substituted 3,3-dimethylcyclopropane-1-carboxylates for their mothproofing efficacy found that the pyrethroids offer good protection against larval damage by the common clothes moth but as a general rule are less effective in their activity to the Anthrenus species. Expand
A new pyrethroid of high insecticidal activity
New pyrethroids containing heterocyclic rings in the alcohol moieties were synthesised and their insecticidal activities were studied. Of these new pyrethroids, 3-benzylpyrrol-1-ylmethyl (1RS-cis,Expand
Neuroreceptor and Behavioral Effects of DDT and Pyrethroids in Immature and Adult Mammals
TLDR
Depending on the use and persistence of DDT in the environment, it will long continue to constitute a subject for research work and risk evaluation. Expand
6—A COMPARISON OF NEW SYNTHETIC PYRETHROIDS FOR THE INDUSTRIAL INSECTPROOFING OF WOOL
An investigation is reported in which five new synthetic pyrethroids were evaluated in the laboratory for their effectiveness as durable insectproofing agents for wool. Their dyebath-exhaustionExpand
New Insecticides. Combined DDT-Isosteres and Pyrethroid Structures
Our structural model for DDT-type insecticides was used to design the DDT isostere 2,2-dimethyl-l,l-bis (4-ethoxyphenyl)cyclopropane which contains the dimethylcyclopropane part-structure ofExpand
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References

SHOWING 1-9 OF 9 REFERENCES
Potent Pyrethroid Insecticides from Modified Cyclopropane Acids
TLDR
It is found that a simple modification of the acid side chain in bioresmethrin by which the four carbon atoms in the isobutenyl group are redisposed to a but-1-enyl substituent produces still greater insecticidal activity whilst retaining low mammalian toxicity. Expand
5-Benzyl-3-furylmethyl Chrysanthemate: a New Potent Insecticide
FOLLOWING earlier work1, we have synthesized more non-ketonic esters of chrysanthemic acid. One new compound, 5-benzyl-3-furylmethyl (+)-trans-chrysanthemate (I), is fifty-five times as toxic toExpand
The relationship between the structure and the activity of pyrethroids.
  • M. Elliott
  • Biology, Medicine
  • Bulletin of the World Health Organization
  • 1971
There is considerable scope for developing new non-persistent insecticides with little hazard for man and mammals by modifying the structures of the natural pyrethrins. New compounds alreadyExpand
The pyrethrins and related compounds. XIII. Insecticidal methyl‐, alkenyl and benzyl‐substituted furfuryl and furylmethyl chrysanthemates
Abstract 3‐Furylmethyl and furfuryl chrysanthemates with methyl, benzyl, substituted benzyl and alkenyl substituents, and other heterocyclic analogues of these compounds, are synthesised forExpand
Toxicity of natural and synthetic pyrethrins to rats
Abstract Natural pyrethrins and five synthetic analogs were given intravenously and orally to rats. All the compounds were much more toxic by the intravenous route, but the ratio of the acuteExpand
The Differential Calorimetric Study of the Reactivity of Unstable Compounds
The detection of unstable intermediates in chemical, photochemical, and radiation-chemical reactions can be greatly facilitated by the use of thermoanalytical methods. Special advantages are offeredExpand