A Photostable Pyrethroid

@article{Elliott1973APP,
  title={A Photostable Pyrethroid},
  author={Michael Elliott and Andrew W. Farnham and Norman Frank Janes and P. H. Needham and David A. Pulman and John H. Stevenson},
  journal={Nature},
  year={1973},
  volume={246},
  pages={169-170}
}
THE natural pyrethrins (see refs 1 and 2 for references) (for example, pyrethrin I (1)) and related synthetic insecticides3 (allethrin (2), bioallethrin (3), resmethrin (4), bioresmethrin (5), Cismethrin (6) and the ethanochrysanthemate (7)) are unstable in air and light (see refs 1 and 2 for references, and ref. 4). This property restricts their use, particularly against pests of agricultural crops, in spite of other favourable characteristics (see refs 1–3 for references) (outstanding potency… 

Action of pyrethroids.

Effects of synthetic pyrethroid insecticides on nontarget organisms.

Synthetic pyrethroids are much less persistent than the organochlorine insecticides, such as DDT and dieldrin, and apparently do not accumulate in the environment.

Metabolic considerations in pyrethroid design.

  • D. M. Soderlund
  • Biology
    Xenobiotica; the fate of foreign compounds in biological systems
  • 1992
The evolutionary development of the pyrethroids illustrates how knowledge of metabolic fate can contribute to the design of novel insecticides with improved insecticidal activity and selective toxicity.

Properties and applications of pyrethroids.

  • M. Elliott
  • Biology, Medicine
    Environmental health perspectives
  • 1976
Initial tests indicate that even the more stable compounds are degraded rapidly in soil, so if the trials at present in progress reveal no toxicological or environmental hazards, within a few years synthetic pyrethroids should be available to control a wide range of domestic, veterinary, horticultural, agricultural, and forest pests at low rates of application.

Deltamethrin: the cream of the crop.

  • D. Pulman
  • Biology, Chemistry
    Journal of agricultural and food chemistry
  • 2011
Second-generation pyrethroids with improved potency and photostability suitable for agricultural use and introduction of novel substituents at the 3-position of the cyclopropane ring then led to the discovery of insecticidally active compounds with greatly improved potency.

Beta-cyfluthrin, a synthetic pyrethroid for mosquito control.

  • V. VasukiA. Rajavel
  • Medicine, Biology
    The Southeast Asian journal of tropical medicine and public health
  • 1992
Beta-cyfluthrin is a good insecticide for mosquito control, however, care should be exercised while using it as a larvicide in breeding habitats considering its toxicity to fish.

Resmethrin, the first modern pyrethroid insecticide.

The discovery of resmethrin almost five decades ago was the seminal event in the development of pyrethroid insecticides as important pest management tools, the value of which endures to this day.

The Biological Evaluation of Pyrethroids as Potential Mothproofing Agents

Evaluating different classes of 2-substituted 3,3-dimethylcyclopropane-1-carboxylates for their mothproofing efficacy found that the pyrethroids offer good protection against larval damage by the common clothes moth but as a general rule are less effective in their activity to the Anthrenus species.

A new pyrethroid of high insecticidal activity

New pyrethroids containing heterocyclic rings in the alcohol moieties were synthesised and their insecticidal activities were studied. Of these new pyrethroids, 3-benzylpyrrol-1-ylmethyl (1RS-cis,

Neuroreceptor and Behavioral Effects of DDT and Pyrethroids in Immature and Adult Mammals

Depending on the use and persistence of DDT in the environment, it will long continue to constitute a subject for research work and risk evaluation.
...

References

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It is found that a simple modification of the acid side chain in bioresmethrin by which the four carbon atoms in the isobutenyl group are redisposed to a but-1-enyl substituent produces still greater insecticidal activity whilst retaining low mammalian toxicity.

5-Benzyl-3-furylmethyl Chrysanthemate: a New Potent Insecticide

The (±)-cis-trans-clarysanthemate (m.p. 43–48°) is the most toxic compound tested so far, of any class of insecticide, to 1–2 day old unfed females of Anopheles stephensi and Aedes aegypti.

The relationship between the structure and the activity of pyrethroids.

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  • Biology
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There is considerable scope for developing new non-persistent insecticides with little hazard for man and mammals by modifying the structures of the natural pyrethrins. New compounds already

The pyrethrins and related compounds. XIII. Insecticidal methyl‐, alkenyl and benzyl‐substituted furfuryl and furylmethyl chrysanthemates

Abstract 3‐Furylmethyl and furfuryl chrysanthemates with methyl, benzyl, substituted benzyl and alkenyl substituents, and other heterocyclic analogues of these compounds, are synthesised for

The Differential Calorimetric Study of the Reactivity of Unstable Compounds

The detection of unstable intermediates in chemical, photochemical, and radiation-chemical reactions can be greatly facilitated by the use of thermoanalytical methods. Special advantages are offered

A photostable pyrethroid.

  • 1973