A Phase II Clinical Trial of Flutamide in the Treatment of Advanced Breast Cancer

@article{Zhao1988API,
  title={A Phase II Clinical Trial of Flutamide in the Treatment of Advanced Breast Cancer},
  author={Tiping Zhao and G F He},
  journal={Tumori Journal},
  year={1988},
  volume={74},
  pages={53 - 56}
}
  • T. Zhao, G. He
  • Published 1 February 1988
  • Medicine, Biology
  • Tumori Journal
An antiandrogenic agent flutamide was used in the treatment of one male and 14 female postmenopausal breast cancer patients. Only a mild and transient response was seen in 2 female patients. Therefore, flutamide cannot be used solely in the treatment of female postmenopausal breast cancer. 
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Results Citations
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13 Citations

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Role of the androgen receptor in triple-negative breast cancer.
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The antiproliferative effect of hydroxyflutamide, without virilizing side-effects, suggests that it is worth exploring its possible employment together with antioestrogens in the treatment of breast cancer patients.
The Role of Androgen Receptor in Breast Cancer.
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The Role of Androgen Receptor Signalling in Endocrine Resistant Breast Cancer
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Understanding of the role of the AR in BCa progression is further understood and it is suggested that it is a valid therapeutic target to prevent and/or treat endocrine resistant disease.
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