A Phase I Trial of Thermal Sensitization Using Induced Oxidative Stress in the Context of HIPEC

@article{Harrison2013API,
  title={A Phase I Trial of Thermal Sensitization Using Induced Oxidative Stress in the Context of HIPEC},
  author={Lawrence E. Harrison and Greg Tiesi and Reza Razavi and DO Chia-ChiWang},
  journal={Annals of Surgical Oncology},
  year={2013},
  volume={20},
  pages={1843-1850}
}
Inducing oxidative stress under hyperthermic conditions significantly decreases tumor cell growth in a murine model of human colon cancer carcinomatosis. This phase I study examines the safety and pharmacokinetics of induced oxidative stress by the addition of hydrogen peroxide (H2O2) to the perfusate in patients undergoing cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC) for advanced abdominal-only malignancies. Patients with advanced colon or appendiceal malignancies… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 26 references

Similar Papers

Loading similar papers…