A Phase 2 Multi-center, Open-label, Switch-over Trial to Evaluate the Safety and Efficacy of Abcertin® in Patients with Type 1 Gaucher Disease

@article{Choi2015AP2,
  title={A Phase 2 Multi-center, Open-label, Switch-over Trial to Evaluate the Safety and Efficacy of Abcertin{\textregistered} in Patients with Type 1 Gaucher Disease},
  author={Jin-Ho Choi and Beom Hee Lee and Jung min Ko and Young Bae Sohn and Jin-Sung Lee and Gu-Hwan Kim and Sun-Hee Heo and June-Young Park and Yoo Mi Kim and Ja-Hye Kim and Han-Wook Yoo},
  journal={Journal of Korean Medical Science},
  year={2015},
  volume={30},
  pages={378 - 384}
}
Gaucher disease is a lysosomal storage disease for which enzyme replacement therapy has proven to be effective. A switch-over clinical trial was performed to evaluate the efficacy and safety of Abcertin® (ISU Abxis, Seoul, Korea) in subjects with type 1 Gaucher disease who were previously treated with imiglucerase. Five Korean patients with type 1 Gaucher disease were enrolled. Previous doses of imiglucerase ranged from 30 to 55 U/kg every other week. The same dose of Abcertin® was administered… 
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