A Pax3/Pax7-dependent population of skeletal muscle progenitor cells

@article{Relaix2005APP,
  title={A Pax3/Pax7-dependent population of skeletal muscle progenitor cells},
  author={F. Relaix and D. Rocancourt and A. Mansouri and M. Buckingham},
  journal={Nature},
  year={2005},
  volume={435},
  pages={948-953}
}
During vertebrate development, successive phases of embryonic and fetal myogenesis lead to the formation and growth of skeletal muscles. Although the origin and molecular regulation of the earliest embryonic muscle cells is well understood, less is known about later stages of myogenesis. We have identified a new cell population that expresses the transcription factors Pax3 and Pax7 (paired box proteins 3 and 7) but no skeletal-muscle-specific markers. These cells are maintained as a… Expand
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