A Parsimony Approach to Genome-Wide Ortholog Assignment

Abstract

The assignment of orthologous genes between a pair of genomes is a fundamental and challenging problem in comparative genomics, since many computational methods for solving various biological problems critically rely on bona fide orthologs as input. While it is usually done using sequence similarity search, we recently proposed a new combinatorial approach… (More)
DOI: 10.1007/11732990_47

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