A PTBA small molecule enhances recovery and reduces postinjury fibrosis after aristolochic acid-induced kidney injury.

Abstract

Phenylthiobutanoic acids (PTBAs) are a new class of histone deacetylase (HDAC) inhibitors that accelerate recovery and reduce postinjury fibrosis after ischemia-reperfusion-induced acute kidney injury. However, unlike the more common scenario in which patients present with protracted and less clearly defined onset of renal injury, this model of acute kidney… (More)
DOI: 10.1152/ajprenal.00534.2013

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@article{Novitskaya2014APS, title={A PTBA small molecule enhances recovery and reduces postinjury fibrosis after aristolochic acid-induced kidney injury.}, author={Tatiana Novitskaya and Lee A. McDermott and Ke Xin Zhang and Takuto Chiba and Paisit Paueksakon and Neil A. Hukriede and Mark P. de Caestecker}, journal={American journal of physiology. Renal physiology}, year={2014}, volume={306 5}, pages={F496-504} }