• Medicine
  • Published in
    The Journal of experimental…
    1972

A PREALBUMIN ACTIVATOR OF PREKALLIKREIN

@article{Kaplan1972APA,
  title={A PREALBUMIN ACTIVATOR OF PREKALLIKREIN },
  author={Allen P Kaplan and A Barry Kay and K Frank Austen},
  journal={The Journal of Experimental Medicine},
  year={1972},
  volume={135},
  pages={81 - 97}
}
Human plasma kallikrein has been shown to directly and selectively attract human neutrophils from a mixed leukocyte population. The capacity of plasma kallikrein to be chemotactic and to generate the nonapeptide bradykinin was maintained during progressive purification. While neither highly purified prekallikrein nor the prealbumin Hageman factor fragments were chemotactic alone, their interaction so as to convert prekallikrein to kallikrein yielded both chemotactic and kinin-generating… CONTINUE READING

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THE FIRST COMPONENT OF THE KININ-FORMING SYSTEM IN HUMAN AND RABBIT PLASMA

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A prealbumin activator of prekallikrein

A. P. Kaplan, K. F. Austen
  • J. Exp. Meal
  • 1970
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