A PLA1-2 punch regulates the Golgi complex.

  title={A PLA1-2 punch regulates the Golgi complex.},
  author={Marie E Bechler and Paul de Figueiredo and William J. Brown},
  journal={Trends in cell biology},
  volume={22 2},
The mammalian Golgi complex, trans Golgi network (TGN) and ER-Golgi intermediate compartment (ERGIC) are comprised of membrane cisternae, coated vesicles and membrane tubules, all of which contribute to membrane trafficking and maintenance of their unique architectures. Recently, a new cast of players was discovered to regulate the Golgi and ERGIC: four unrelated cytoplasmic phospholipase A (PLA) enzymes, cPLA(2)α (GIVA cPLA(2)), PAFAH Ib (GVIII PLA(2)), iPLA(2)-β (GVIA-2 iPLA(2)) and iPLA(1… CONTINUE READING


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Functional Characterization of Mutations in Inherited Human cPLA2 Deficiency

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  • 2011
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