A PCR-based test suitable for screening for fragile X syndrome among mentally retarded males


Ever since the identification of the genetic cause of fragile X syndrome as the expansion of an unstable trinucleotide sequence, several diagnostic strategies have evolved from molecular studies. However, we still lack a simple test suitable for population screening. We have therefore developed a nonisotopic polymerase chain reaction (PCR)-based technique… (More)
DOI: 10.1007/BF02346194


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