A PAMPA Study of the Permeability‐Enhancing Effect of New Ceramide Analogues

@article{Sink2009APS,
  title={A PAMPA Study of the Permeability‐Enhancing Effect of New Ceramide Analogues},
  author={B. Sink{\'o} and J. K{\"o}k{\"o}si and A. Avdeef and K. Tak{\'a}cs‐Nov{\'a}k},
  journal={Chemistry \& Biodiversity},
  year={2009},
  volume={6}
}
There is a major need in drug discovery for quick, precise, and cost‐effective high‐throughput screening (HTS) systems in the early stages of drug research. The Parallel Artificial Membrane Permeability Assay (PAMPA) aims at predicting the passive membrane properties of drugs. Since 1998, model membranes have been developed to predict gastro‐intestinal absorption or transport through the blood–brain barrier. This paper presents recent results in a project aiming to improve the prediction of… Expand
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