A P2X7 receptor stimulates plasma membrane trafficking in the FRTL rat thyrocyte cell line.

@article{Kochukov2004APR,
  title={A P2X7 receptor stimulates plasma membrane trafficking in the FRTL rat thyrocyte cell line.},
  author={Mikhail Y Kochukov and Aileen K. Ritchie},
  journal={American journal of physiology. Cell physiology},
  year={2004},
  volume={287 4},
  pages={C992-C1002}
}
Thyroid cells express a variety of P2Y and P2X purinergic receptor subtypes. G protein-coupled P2Y receptors influence a wide variety of thyrocyte-specific functions; however, functional P2X receptor-gated channels have not been observed. In this study, we used whole cell patch-clamp recording and fluorescence imaging of the plasma membrane marker FM1-43 to examine the effects of extracellular ATP on membrane permeability and trafficking in the Fisher rat thyroid cell line FRTL. We found a… CONTINUE READING

Citations

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P2X receptor channels in endocrine glands.

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P2X7 receptor: Death or life?

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