A Novel and Rapid Method to Determine Doxycycline in Human Plasma by Liquid Chromatography Tandem Mass Spectrometry

@inproceedings{Krishna2012ANA,
  title={A Novel and Rapid Method to Determine Doxycycline in Human Plasma by Liquid Chromatography Tandem Mass Spectrometry},
  author={A. Chaitanya Krishna and Munusamy Sathiyaraj and R Sanjeev Saravanan and R. Chelladurai and R. Vignesh},
  booktitle={Indian journal of pharmaceutical sciences},
  year={2012}
}
A simple, rapid, specific and sensitive liquid chromatography tandem mass spectrometric method has been developed and validated for the determination of doxycycline from the human plasma. Doxycycline is extracted from human plasma by solid phase extraction. Demeclocycline was used as an internal standard. Detection was performed at transitions of 444.800… CONTINUE READING