A Novel Therapy for Melanoma Developed in Mice: Transformation of Melanoma into Dendritic Cells with Listeria monocytogenes

@inproceedings{BronchaloVicente2015ANT,
  title={A Novel Therapy for Melanoma Developed in Mice: Transformation of Melanoma into Dendritic Cells with Listeria monocytogenes},
  author={Luc{\'i}a Bronchalo-Vicente and Estela Rodr{\'i}guez-Del R{\'i}o and Javier Freire and Ricardo Calder{\'o}n-Gonz{\'a}lez and Elisabet Frande-Cabanes and Jos{\'e} Javier G{\'o}mez-Rom{\'a}n and H{\'e}ctor Fern{\'a}ndez-Llaca and Sons{\'o}les Ya{\~n}ez-Diaz and Carmen {\'A}lvarez-Dom{\'i}nguez},
  booktitle={PloS one},
  year={2015}
}
Listeria monocytogenes is a gram-positive bacteria and human pathogen widely used in cancer immunotherapy because of its capacity to induce a specific cytotoxic T cell response in tumours. This bacterial pathogen strongly induces innate and specific immunity with the potential to overcome tumour induced tolerance and weak immunogenicity. Here, we propose a Listeria based vaccination for melanoma based in its tropism for these tumour cells and its ability to transform in vitro and in vivo… CONTINUE READING
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Melanoma-infiltrating dendritic cells

Oncoimmunology • 2012
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