A Novel Tandem Reporter Quantifies RNA Polymerase II Termination in Mammalian Cells

Abstract

BACKGROUND Making the correct choice between transcription elongation and transcription termination is essential to the function of RNA polymerase II, and fundamental to gene expression. This choice can be influenced by factors modifying the transcription complex, factors modifying chromatin, or signals mediated by the template or transcript. To aid in the… (More)
DOI: 10.1371/journal.pone.0006193

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