A Novel Synthetic Receptor-Based Immunoassay for Influenza Vaccine Quantification

  title={A Novel Synthetic Receptor-Based Immunoassay for Influenza Vaccine Quantification},
  author={Anwar M Hashem and Caroline Gravel and Aaron Farnsworth and Wei Zou and M Joanne Lemieux and Kangwei Xu and Changgui Li and Jun-Zhi Wang and Marie-France Goneau and Maria Merziotis and RunTao He and Michel Gilbert and Xuguang Li},
  booktitle={PloS one},
Vaccination is the most effective prophylactic method for preventing influenza. Quantification of influenza vaccine antigens is critically important before the vaccine is used for human immunization. Currently the vaccine antigen quantification relies on hemagglutinin content quantification, the key antigenic component, by single radial immunodiffusion (SRID) assay. Due to the inherent disadvantages associated with the traditional SRID; i.e. low sensitivity, low throughput and need for annual… CONTINUE READING
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