A Novel Strategy for Live Detection of Viral Infection in Drosophila melanogaster

Abstract

We have created a transgenic reporter for virus infection, and used it to study Nora virus infection in Drosophila melanogaster. The transgenic construct, Munin, expresses the yeast transcription factor Gal4, tethered to a transmembrane anchor via a linker that can be cleaved by a viral protease. In infected cells, liberated Gal4 will then transcribe any… (More)
DOI: 10.1038/srep26250

Topics

3 Figures and Tables

Slides referencing similar topics