A Novel Rat Model to Study the Role of Intracranial Pressure Modulation on Optic Neuropathies

@inproceedings{Chowdhury2013ANR,
  title={A Novel Rat Model to Study the Role of Intracranial Pressure Modulation on Optic Neuropathies},
  author={Uttio Roy Chowdhury and Bradley H. Holman and Michael P Fautsch},
  booktitle={PloS one},
  year={2013}
}
Reduced intracranial pressure is considered a risk factor for glaucomatous optic neuropathies. All current data supporting intracranial pressure as a glaucoma risk factor comes from retrospective and prospective studies. Unfortunately, there are no relevant animal models for investigating this link experimentally. Here we report a novel rat model that can be used to study the role of intracranial pressure modulation on optic neuropathies. Stainless steel cannulae were inserted into the cisterna… CONTINUE READING
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