A Novel Model of Urinary Tract Differentiation, Tissue Regeneration, and Disease: Reprogramming Human Prostate and Bladder Cells into Induced Pluripotent Stem Cells

@inproceedings{Moad2013ANM,
  title={A Novel Model of Urinary Tract Differentiation, Tissue Regeneration, and Disease: Reprogramming Human Prostate and Bladder Cells into Induced Pluripotent Stem Cells},
  author={Mohammad Moad and Deepali Pal and Anastasia C. Hepburn and Stuart Williamson and Laura E. Wilson and Majlinda Lako and Lyle Armstrong and Simon W Hayward and Omar Enrique Franco and Justin M M Cates and Sarah E. Fordham and Stefan Alexander Przyborski and Jane Carr-Wilkinson and Craig N. Robson and Rakesh Heer},
  booktitle={European urology},
  year={2013}
}
BACKGROUND Primary culture and animal and cell-line models of prostate and bladder development have limitations in describing human biology, and novel strategies that describe the full spectrum of differentiation from foetal through to ageing tissue are required. Recent advances in biology demonstrate that direct reprogramming of somatic cells into pluripotent embryonic stem cell (ESC)-like cells is possible. These cells, termed induced pluripotent stem cells (iPSCs), could theoretically… CONTINUE READING
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