A Novel Immunological Assay for Hepcidin Quantification in Human Serum

@article{Koliaraki2009ANI,
  title={A Novel Immunological Assay for Hepcidin Quantification in Human Serum},
  author={Vasiliki Koliaraki and Martha Marinou and Theodoros Vassilakopoulos and Eustathios Vavourakis and Emmanuel A Tsochatzis and Gerassimos Alexander Pangalis and G V Papatheodoridis and Alexandra Stamoulakatou and Dorine W Swinkels and George Papanikolaou and Avgi Mamalaki},
  journal={PLoS ONE},
  year={2009},
  volume={4},
  pages={7806 - 7810}
}
BACKGROUND Hepcidin is a 25-aminoacid cysteine-rich iron regulating peptide. Increased hepcidin concentrations lead to iron sequestration in macrophages, contributing to the pathogenesis of anaemia of chronic disease whereas decreased hepcidin is observed in iron deficiency and primary iron overload diseases such as hereditary hemochromatosis. Hepcidin quantification in human blood or urine may provide further insights for the pathogenesis of disorders of iron homeostasis and might prove a… CONTINUE READING
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