A Novel Immune Evasion Strategy of Candida albicans: Proteolytic Cleavage of a Salivary Antimicrobial Peptide

@article{Meiller2009ANI,
  title={A Novel Immune Evasion Strategy of Candida albicans: Proteolytic Cleavage of a Salivary Antimicrobial Peptide},
  author={Timothy Francis Meiller and Bernhard Hube and Lydia Schild and Mark E. Shirtliff and Mark A. Scheper and Robert P. Winkler and A P S Ton and Mary Ann Jabra-Rizk},
  journal={PLoS ONE},
  year={2009},
  volume={4},
  pages={80 - 84}
}
Oropharyngeal candidiasis is an opportunistic infection considered to be a harbinger of AIDS. The etiologic agent Candida albicans is a fungal species commonly colonizing human mucosal surfaces. However, under conditions of immune dysfunction, colonizing C. albicans can become an opportunistic pathogen causing superficial or even life-threatening infections. The reasons behind this transition, however, are not clear. In the oral cavity, salivary antimicrobial peptides are considered to be an… CONTINUE READING
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