A Novel Human Glycoprotein ACA is an Upstream Regulator of Human Hematopoiesis

  title={A Novel Human Glycoprotein ACA is an Upstream Regulator of Human Hematopoiesis},
  author={Z. A. Becker-Koji{\'c} and Juan R. Ure{\~n}a-Peralta and Rainer Saffrich and F. J. Rodriguez-Jim{\'e}nez and M. P. Rubio and Pablo R{\'i}os and A. Romero and Anthony Dick Ho and Miodrag Stojkovic},
  journal={Bulletin of Experimental Biology and Medicine},
A central issue in stem cell biology is a better understanding of the molecular mechanisms that regulate self-renewal of human hematopoietic stem cells (HSCs). Control of the specific function of HSCs like self-renewal and differentiation might be regulated by a common set of critical genes. However, the regulation among these genes is yet to be elucidated. Here, we show that activation by a novel human GPI-linked glycoprotein ACA at the surface of human peripheral blood progenitor cells… 



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