A Novel G Protein-Coupled Receptor of Schistosoma mansoni (SmGPR-3) Is Activated by Dopamine and Is Widely Expressed in the Nervous System

@inproceedings{ElShehabi2012ANG,
  title={A Novel G Protein-Coupled Receptor of Schistosoma mansoni (SmGPR-3) Is Activated by Dopamine and Is Widely Expressed in the Nervous System},
  author={Fouad El-Shehabi and Amira Taman and Lorena S. Moali and Nelly El-Sakkary and Paula Ribeiro},
  booktitle={PLoS neglected tropical diseases},
  year={2012}
}
Schistosomes have a well developed nervous system that coordinates virtually every activity of the parasite and therefore is considered to be a promising target for chemotherapeutic intervention. Neurotransmitter receptors, in particular those involved in neuromuscular control, are proven drug targets in other helminths but very few of these receptors have been identified in schistosomes and little is known about their roles in the biology of the worm. Here we describe a novel Schistosoma… CONTINUE READING
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