A Novel Evaluation Method of Gastric Mucoadhesive Property in Vitro and the Mucoadhesive Mechanism of Tetracycline-Sucralfate Acidic Complex for Eradication of Helicobacter pylori


Purpose. The gastric mucoadhesive property of tetracycline-sucralfate acidic complex (CO) was evaluated by using a novel method in vitro to compare with the in vivo test. The mucoadhesive mechanism of the acidic complex was also studied. Methods. The gastric mucosa removed from a rat was placed covering the end of a plunger and secured in a disposable… (More)
DOI: 10.1023/B:PHAM.0000019293.57927.7f

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