A Novel Complotype Combination Associates with Age-Related Macular Degeneration and High Complement Activation Levels in vivo


The complement system is the first line of defense against foreign intruders, and deregulation of this system has been described in multiple diseases. In age-related macular degeneration (AMD), patients have higher complement activation levels compared to controls. Recently, a combination of three single nucleotide polymorphisms (SNPs) in genes of the… (More)
DOI: 10.1038/srep26568


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