A Novel Complex Mutant β-Lactamase, TEM-68, Identified in a Klebsiella pneumoniae Isolate from an Outbreak of Extended-Spectrum β-Lactamase-Producing Klebsiellae

@article{Fiett2000ANC,
  title={A Novel Complex Mutant $\beta$-Lactamase, TEM-68, Identified in a Klebsiella pneumoniae Isolate from an Outbreak of Extended-Spectrum $\beta$-Lactamase-Producing Klebsiellae},
  author={Janusz Fiett and Andrzej Pałucha and Beata Mia˛czyńska and M. Stankiewicz and Hanna Przondo-Mordarska and Waleria Hryniewicz and Marek Gniadkowski},
  journal={Antimicrobial Agents and Chemotherapy},
  year={2000},
  volume={44},
  pages={1499 - 1505}
}
ABSTRACT Twenty-two Klebsiella pneumoniae and two K. oxytoca extended-spectrum β-lactamase (ESBL)-producing isolates were collected in 1996 from patients in two pediatric wards of the University Hospital in Wrocław, Poland. Molecular typing has revealed that the K. pneumoniae isolates represented four different epidemic strains. Three kinds of enzymes with ESBL activity (pI values of 5.7, 6.0, and 8.2) were identified. The pI 6.0 β-lactamases belonged to the TEM family, and sequencing of… Expand
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