A Novel Chemical Solution to Demineralize Vascular Calcification in Ex-Vivo Amputated Limbs

  title={A Novel Chemical Solution to Demineralize Vascular Calcification in Ex-Vivo Amputated Limbs},
  author={Houssam Farres and Mohamad H. Yamani and Soundos K. Moualla and P. A. Fuqua and Albert G. Hakaim},
  journal={Journal of Vascular Medicine \& Surgery},
The study was performed to evaluate the ex-vivo demineralizing efficacy of a novel chemical solution, combined L(+) lactic acid and D-gluconic acid (LAGA), in calcified peripheral arteries of 2 patients who underwent limb amputation. Angiography was obtained at baseline and after local installation of the 20 ml of LAGA solution in the occluded arteries. A significant dissolution of the calcification with restoration of patency of the occluded arteries was noted. LAGA solution is efficacious in… Expand
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