A Novel Brain Neurovascular Unit Model with Neurons, Astrocytes and Microvascular Endothelial Cells of Rat

@inproceedings{Xue2013ANB,
  title={A Novel Brain Neurovascular Unit Model with Neurons, Astrocytes and Microvascular Endothelial Cells of Rat},
  author={Qiang Xue and Yang Liu and Hongyi Qi and Qiang Ma and Ling Xu and Weihai Chen and Gang Chen and Xiaoyu Xu},
  booktitle={International journal of biological sciences},
  year={2013}
}
A novel triple cell neurovascular unit (NVU) model co-culturing with neurons, brain microvascular endothelial cells (BMECs) and astrocytes was established in this study for investigating the cerebral diseases and screening the candidates of therapeutic drug. We have first performed the cell identification and morphological characterization, analyzed the specific protein expression and determined the blood-brain barrier (BBB) function of the co-culture model under normal condition. Then, we… CONTINUE READING
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