A Novel Aerosol Foam Formulation of Calcipotriol and Betamethasone Has No Impact on HPA Axis and Calcium Homeostasis in Patients With Extensive Psoriasis Vulgaris

@inproceedings{Taraska2016ANA,
  title={A Novel Aerosol Foam Formulation of Calcipotriol and Betamethasone Has No Impact on HPA Axis and Calcium Homeostasis in Patients With Extensive Psoriasis Vulgaris},
  author={Victoria Taraska and Raj Tuppal and Martin Olesen and Claus Bang Pedersen and Kim Papp},
  booktitle={Journal of cutaneous medicine and surgery},
  year={2016}
}
BACKGROUND Fixed combination calcipotriol 50 µg/g (Cal; as hydrate) plus betamethasone 0.5 mg/g (as dipropionate; BD) has been formulated in an innovative aerosol foam. OBJECTIVE To assess systemic safety of Cal/BD aerosol foam. METHODS In a multicentre, single-arm, open-label, maximal-use systemic-exposure trial, adult patients with moderate to severe, extensive psoriasis (15%-30% of body surface area, including ≥30% of scalp) applied Cal/BD foam once daily. Endpoints were week 4 abnormal… CONTINUE READING