A Novel , 11 Nucleotide Variant of w , w * : One of a Class of Sequences Defining the Escherichia coli Recombination Hotspot


0022-2836/00/030469±11 $35.00/0 In wild-type Escherichia coli, recognition of the recombination hotspot, w (50-GCTGGTGG-30), by the RecBCD enzyme is central to homologous recombination. However, in the recC* class of RecBCD mutants, stimulation of recombination by the canonical w sequence is not detectable, but the levels of homologous recombination are… (More)

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