A Notch-independent function of Suppressor of Hairless during the development of the bristle sensory organ precursor cell of Drosophila.

@article{Koelzer2003ANF,
  title={A Notch-independent function of Suppressor of Hairless during the development of the bristle sensory organ precursor cell of Drosophila.},
  author={Stefan Koelzer and Thomas M Klein},
  journal={Development},
  year={2003},
  volume={130 9},
  pages={1973-88}
}
Su(H)/CBF1 is a key component of the evolutionary conserved Notch signalling pathway. It is a transcription factor that acts as a repressor in the absence of the Notch signal. If Notch signalling is activated, it associates with the released intracellular domain of the Notch receptor and acts as an activator of transcription. During the development of the mechanosensory bristles of Drosophila, a selection process called lateral inhibition assures that only a few cells are selected out of a… CONTINUE READING

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in Drosophila

  • T. Klein
  • 2002

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