A Noninvasive Genetic/Pharmacologic Strategy for Visualizing Cell Morphology and Clonal Relationships in the Mouse

@article{Badea2003ANG,
  title={A Noninvasive Genetic/Pharmacologic Strategy for Visualizing Cell Morphology and Clonal Relationships in the Mouse},
  author={T. Badea and Y. Wang and J. Nathans},
  journal={The Journal of Neuroscience},
  year={2003},
  volume={23},
  pages={2314 - 2322}
}
  • T. Badea, Y. Wang, J. Nathans
  • Published 2003
  • Biology, Medicine
  • The Journal of Neuroscience
  • Analysis of cellular morphology is the most general approach to neuronal classification. With the increased use of genetically engineered mice, there is a growing need for methods that can selectively visualize the morphologies of specified subsets of neurons. This capability is needed both to define cell morphologic phenotypes and to mark cells in a noninvasive manner for lineage studies. To this end, we describe a bipartite genetic system based on a Cre-estrogen receptor (ER) fusion protein… CONTINUE READING
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