A Non-Synonymous HMGA2 Variant Decreases Height in Shetland Ponies and Other Small Horses

@inproceedings{Frischknecht2015ANH,
  title={A Non-Synonymous HMGA2 Variant Decreases Height in Shetland Ponies and Other Small Horses},
  author={Mirjam Frischknecht and Vidhya Jagannathan and Philippe Plattet and Markus Neuditschko and Heidi Signer-Hasler and Iris I Bachmann and Alicja Pacholewska and Cord Dr{\"o}gem{\"u}ller and Elisabeth Dietschi and Christine Flury and Stefan Rieder and Tosso Leeb and Claire Wade},
  booktitle={PloS one},
  year={2015}
}
The identification of quantitative trait loci (QTL) such as height and their underlying causative variants is still challenging and often requires large sample sizes. In humans hundreds of loci with small effects control the heritable portion of height variability. In domestic animals, typically only a few loci with comparatively large effects explain a major fraction of the heritability. We investigated height at withers in Shetland ponies and mapped a QTL to ECA 6 by genome-wide association… CONTINUE READING