A New Zebrafish Model of Oro-Intestinal Pathogen Colonization Reveals a Key Role for Adhesion in Protection by Probiotic Bacteria

@inproceedings{Rendueles2012ANZ,
  title={A New Zebrafish Model of Oro-Intestinal Pathogen Colonization Reveals a Key Role for Adhesion in Protection by Probiotic Bacteria},
  author={Olaya Rendueles and Lionel Ferri{\`e}res and Maxence Fr{\'e}taud and Ev{\'e}lyne B{\'e}gaud and Philippe Herbomel and J. -P. Levraud and Jean-Marc Ghigo},
  booktitle={PLoS pathogens},
  year={2012}
}
The beneficial contribution of commensal bacteria to host health and homeostasis led to the concept that exogenous non-pathogenic bacteria called probiotics could be used to limit disease caused by pathogens. However, despite recent progress using gnotobiotic mammal and invertebrate models, mechanisms underlying protection afforded by commensal and probiotic bacteria against pathogens remain poorly understood. Here we developed a zebrafish model of controlled co-infection in which germ-free… CONTINUE READING

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