A New Trick of an Old Molecule: Androgen Receptor Splice Variants Taking the Stage?!

Abstract

Prostate cancer is the second leading cause of cancer-related death in American men. Although most prostate cancers are initially androgen-dependent and respond to androgen ablation therapy, majority of them eventually relapse and progress into incurable castration-resistant (or hormone refractory) prostate cancer. The underlying mechanisms are the focus of… (More)

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