A New Subdivision, Marginal Division, in the Neostriatum of the Monkey Brain

@article{Shu2004ANS,
  title={A New Subdivision, Marginal Division, in the Neostriatum of the Monkey Brain},
  author={Siyun Shu and Xin-min Bao and C Zhang and S. X. Li and Wood Yee Chan and David T. Yew},
  journal={Neurochemical Research},
  year={2004},
  volume={25},
  pages={231-237}
}
A new subdivision, the “marginal division” (MrD), was discovered at the caudal border of the striatum and surrounds the rostral edge of the globus pallidus in the rat brain in our previous studies. The neuronal somata of the MrD are mostly fusiform in shape with their long axes lining dorsoventrally. The MrD is more densely filled with substance P (SP)-, Leucine-enkephalin (L-Enk)-, dynorphin B-, neurotensin-, somatostatin- and cholecystokinin (CCK)-immunoreactive fibers and terminal-like… 

Marginal Division of the Neostriatum: A Subcortical Memory Center

  • S. Shu
  • Biology
    Journal of Biomedical Science
  • 2003
TLDR
In conclusion, based on the position of the MrD, its advanced development in higher mammalian brains, abundant blood supply and diverse connections with other memory-related structures, MrD is likely to be an important subcortical center of learning and memory.

Marginal division of the neostriatum: a subcortical memory center.

  • S. Shu
  • Biology
    Journal of biomedical science
  • 2003
TLDR
In conclusion, based on the position of the MrD, its advanced development in higher mammalian brains, abundant blood supply and diverse connections with other memory-related structures, MrD is likely to be an important subcortical center of learning and memory.

A New Neural Pathway from the Ventral Striatum to the Nucleus Basalis of Meynert with Functional Implication to Learning and Memory

TLDR
Evidence is provided to support the hypothesis that the MrD and the NBM were structurally connected at cellular and subcellular levels with functional implications in learning and memory and suggest reciprocal cholinergic connections between theMrD of the ventral striatum and theNBM, and implicate a role of the Mrd-NBM pathway in learningand memory.

A new area in the human brain associated with learning and memory: immunohistochemical and functional MRI analysis

TLDR
The results of the present investigation indicate the existence of a new area associated with learning and memory function in the human brain, the marginal division (MrD), which probably plays an important role in the execution of digital working memory and appears to link the limbic system and the basal nucleus of Meynert.

The Role of Substance P in the Marginal Division of the Neostriatum in Learning and Memory is Mediated Through the Neurokinin 1 Receptor in Rats

TLDR
NK1R mediates the role of SP in the MrD in learning and memory and knocking down NK1R activity in theMrD by using an antisense oligonucleotide against NK1 R mRNA inhibitedLearning and memory in a Y-maze behavioral test.

Topography and chemoarchitecture of the striatum and pallidum in a monotreme, the short-beaked echidna (Tachyglossus aculeatus)

  • K. Ashwell
  • Biology
    Somatosensory & motor research
  • 2008
TLDR
The observations indicate that the same broad features of striatal and pallidal organization apply across all mammals and suggest that these common features may have arisen before the divergence of the monotreme and therian lineages.

Interactions among memory‐related centers in the brain

TLDR
It is proposed that there are very possibly hierachical memory centers in the brain, based on its position, advanced development in higher mammalian brains, abundant and swift blood supply, and complex connections, to be an important subcortical memory center in thebrain.

Similar effects of substance P on learning and memory function between hippocampus and striatal marginal division

TLDR
Results indicate that the marginal division of the striatum plays a similar function in learning and memory to the hippocampus, which is a valuable addition to the mechanistic understanding of the learning andMemory functions of the marginal Division of the Striatum.

[Age-related changes in resting functional connectivity of the marginal division of the neostriatum in healthy adults].

TLDR
An increased age is associated with alterations in the functional connectivity related with the MrD in healthy adults using resting-state functional magnetic resonance imaging (rs-fMRI).

Altered functional connectivity of the marginal division in Alzheimer's disease.

TLDR
The results suggest that the marginal division functional network is disrupted during Alzheimer's disease, and the functional connectivity between the MrD and the identified regions was significantly correlated with the neuropsychological scores among the MCI and AD subjects.

References

SHOWING 1-10 OF 31 REFERENCES

The 'marginal division': a new subdivision in the neostriatum of the rat.

TLDR
The marginal division of the striatum is a distinct subdivision of the neostriatum based on its cellular morphology, immunohistochemistry and projection pattern.

The 'marginal division': a new subdivision in the neostriatum of the rat.

TLDR
The marginal division of the striatum is a distinct subdivision of the neostriatum based on its cellular morphology, immunohistochemistry and projection pattern.

Functions of the basal ganglia

TLDR
This suggestion is strengthened by evidence that the ‘limbic striatum’ seems enabled by its striatonigral efferents to modulate not only the source of its own dopamine innervation but also that of a large additional striatal region.

Pedunculopontine nucleus in the squirrel monkey: Projections to the basal ganglia as revealed by anterograde tract‐tracing methods

TLDR
The results reveal that the PPN gives rise to a massive and highly ordered innervation of the basal ganglia in the squirrel monkey, and this nucleus may act as an important relay in the basal Ganglia circuitry in primates.

Afferent and efferent relationships of the basal ganglia.

TLDR
This suggestion is strengthened by evidence that the 'limbic striatum' seems enabled by its striatonigral efferents to modulate not only the source of its own dopamine innervation but also that of a large additional striatal region.

Organization of intrahippocampal projections originating from CA3 pyramidal cells in the rat

TLDR
The distribution of intrahippocampal projections arising from the CA3 region of the rat hippocampus was investigated using in vitro and in vivo methods and bore numerous varicosities that electron microscopy confirmed to be presynaptic boutons.

Piecing together the puzzle of basal forebrain anatomy.

TLDR
The basal forebrain contains a seemingly heterogeneous collection of structures including nucleus accumbens, olfactory tubercle, septum, diagonal band nuclei, bed nucleus of stria terminalis, substantia innominata, Olfactory cortex, hippocampus formation and amygdaloid body which are characterized foremost by their relation to the hypothalamus, a major regulator of autonomic and endocrine functions.

First visualization of dopaminergic neurons with a monoclonal antibody to dopamine: a light and electron microscopic study.

TLDR
This DA monoclonal antibody seems to be a selective and sensitive tool for studying the dopaminergic neuronal circuitry at both histological and ultrastructural level.

Distribution of alpha 2A-adrenergic receptor-like immunoreactivity in the rat central nervous system.

TLDR
The results provide an extensive immunohistochemical cartography of alpha 2-ARs in the adult rat central nervous system and find perikaryal labeling was diffuse and/or punctate and immunoreactive puncta were heterogeneous in size and number in a region-specific manner.

Nociceptive responses in the neostriatum and globus pallidus of the anesthetized rat.

TLDR
A large proportion of somatosensory neurons within the neostriatum and globus pallidus of anesthetized rats receive nociceptive information, and individual stimulus-response functions of nOCiceptive neurons were best fit by a negatively accelerating (logarithmic) curves.