A New Mutation Affecting FRQ-Less Rhythms in the Circadian System of Neurospora crassa

@inproceedings{Li2011ANM,
  title={A New Mutation Affecting FRQ-Less Rhythms in the Circadian System of Neurospora crassa},
  author={Sanshu Li and Kamyar Motavaze and Elizabeth Kafes and Sujiththa Suntharalingam and Patricia Lakin-Thomas},
  booktitle={PLoS genetics},
  year={2011}
}
We are using the fungus Neurospora crassa as a model organism to study the circadian system of eukaryotes. Although the FRQ/WCC feedback loop is said to be central to the circadian system in Neurospora, rhythms can still be seen under many conditions in FRQ-less (frq knockout) strains. To try to identify components of the FRQ-less oscillator (FLO), we carried out a mutagenesis screen in a FRQ-less strain and selected colonies with altered conidiation (spore-formation) rhythms. A mutation we… CONTINUE READING
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