A New Multigene Family of Putative Pheromone Receptors

@article{Ryba1997ANM,
  title={A New Multigene Family of Putative Pheromone Receptors},
  author={N. Ryba and R. Tirindelli},
  journal={Neuron},
  year={1997},
  volume={19},
  pages={371-379}
}
The vomeronasal organ (VNO) mediates detection of pheromones related to social and reproductive behavior in most terrestrial vertebrates. We have identified a new multigene family of G protein-linked receptors (V2Rs) that are specifically expressed in the VNO. V2Rs have no significant homology to other putative pheromone receptors (V1Rs) or to olfactory receptors but are related to the Ca2+-sensing receptor and metabotropic glutamate receptors. V2Rs are expressed at high levels in small… Expand
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  • 2000
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Recent evidence on VR repertoire contraction/expansion in vertebrates is reviewed and the association between VNO development and VR repertoire size is assessed. Expand
Co-Expression of Putative Pheromone Receptors in the Sensory Neurons of the Vomeronasal Organ
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