A New Method of the Visualization of the Double-Stranded Mitochondrial and Nuclear DNA

Abstract

The study describes the method of a sensitive detection of double-stranded DNA molecules in situ. It is based on the oxidative attack on the deoxyribose moiety by copper(I) in the presence of oxygen. We have shown previously that the oxidative attack leads to the formation of frequent gaps in DNA. Here we have demonstrated that the gaps can be utilized as… (More)
DOI: 10.1371/journal.pone.0066864

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Cite this paper

@inproceedings{Ligasov2013ANM, title={A New Method of the Visualization of the Double-Stranded Mitochondrial and Nuclear DNA}, author={Anna Ligasov{\'a} and Dmytro Strunin and Karel Koberna}, booktitle={PloS one}, year={2013} }