A New Lignan Derivative, Lasiocarpone, from The Stembark of Chisocheton iasiocarpus (Meliaceae)

@article{Hidayat2018ANL,
  title={A New Lignan Derivative, Lasiocarpone, from The Stembark of Chisocheton iasiocarpus (Meliaceae)},
  author={Ace Tatang Hidayat and Nurlelasari Nurlelasari and Fajar Fauzi Abdullah and Desi Harneti and Rani Maharani and Kansy Haikal and Unang Supratman and M. N. Azmi},
  journal={Oriental Journal of Chemistry},
  year={2018}
}
A new lignan derivative, named lasiocarpone (1), was isolated from the stembark of Chisocheton lasiocarpus. The chemical structure of 1 was determined by extensive NMR and MS spectra analyses as well as by comparing with analogue compound from previous studies. Lasiocarpone showed moderate cytotoxic activity against MCF7 breast cancer cells with an IC50 value of 42.5 mM. 
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