A New Chalcone and Antioxidant Constituents of Glycyrrhiza glabra

@article{Chen2017ANC,
  title={A New Chalcone and Antioxidant Constituents of Glycyrrhiza glabra},
  author={Jih-Jung Chen and M. Cheng and Chih-Wen Shu and P. Sung and Y. Lim and L. Cheng and Sin-Ling Wang and Li-Chai Chen},
  journal={Chemistry of Natural Compounds},
  year={2017},
  volume={53},
  pages={632-634}
}
A new chalcone, glycyglabrone (1), has been isolated from the roots of Glycyrrhiza glabra, together with three known compounds, licoagrochalcone B (2), licochalcone C (3), and kanzonol Y (4). The structure of the new compound 1 was determined through spectroscopic and MS analyses. Glycyglabrone (1) and licochalcone C (3) exhibited potent free radical scavenging activity, with IC0.200 values of 4.6 ± 0.6 and 8.2 ± 0.9 μM, respectively, in the diphenylpicrylhydrazyl radical (DPPH) decoloration… Expand
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