A New Benzopyranyl Cadenane Sesquiterpene and Other Antiplasmodial and Cytotoxic Metabolites from Cleistochlamys kirkii

@article{Nyandoro2019ANB,
  title={A New Benzopyranyl Cadenane Sesquiterpene and Other Antiplasmodial and Cytotoxic Metabolites from Cleistochlamys kirkii},
  author={Stephen S Nyandoro and Gasper Maeda and Joan J. E. Munissi and Amra Gruhonjic and P. Fitzpatrick and S. Lindblad and S. Duffy and J. Pelletier and F. Pan and R. Puttreddy and V. Avery and M. Erd{\'e}lyi},
  journal={Molecules},
  year={2019},
  volume={24}
}
  • Stephen S Nyandoro, Gasper Maeda, +9 authors M. Erdélyi
  • Published 2019
  • Chemistry, Medicine
  • Molecules
  • Phytochemical investigations of ethanol root bark and stem bark extracts of Cleistochlamys kirkii (Benth.) Oliv. (Annonaceae) yielded a new benzopyranyl cadinane-type sesquiterpene (cleistonol, 1) alongside 12 known compounds (2-13). The structures of the isolated compounds were established from NMR spectroscopic and mass spectrometric analyses. Structures of compounds 5 and 10 were further confirmed by single crystal X-ray crystallographic analyses, which also established their absolute… CONTINUE READING
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