A New Approach to Flux Coupling Analysis of Metabolic Networks

@inproceedings{Larhlimi2006ANA,
  title={A New Approach to Flux Coupling Analysis of Metabolic Networks},
  author={Abdelhalim Larhlimi and Alexander Bockmayr},
  booktitle={CompLife},
  year={2006}
}
Flux coupling analysis is a method to identify blocked and coupled reactions in a metabolic network at steady state. We present a new approach to flux coupling analysis, which uses a minimum set of generators of the steady state flux cone. Our method does not require to reconfigure the network by splitting reversible reactions into forward and backward reactions. By distinguishing different types of reactions (irreversible, pseudo-irreversible, fully reversible), we show that reaction coupling… CONTINUE READING

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